Gene Therapy Success
A group of researchers at Mount Sinai School of Medicine have discovered a gene therapy
to successfully treat heart failure.
The product that is assisting the enzyme that promotes an ailing heart to pump more efficiently is called
SERCA2a made by MYDICAR.
The gene SERCA2a was created by a team led by Roger J. Hajjar, MD, Research Director of Mount Sinai’s Wiener
Family Cardiovascular Research Laboratories and the Arthur & Janet Ross Professor of Cardiology, Medicine, and
Gene and Cell Medicine at Mount Sinai School of Medicine.
The team did early in 1999 identify the potentials of
SERCA2a as a gene therapy treatment.
Studies have been shown time and time again that SERCA2a is aiding to stop the severity of heart failure. This type
of gene therapy has been announced to medical societies and cardiology professionals all over the world that
research proves that this therapy can treat patients that have advanced heart failure safe and effectively.
Study trials were preformed on a group of 39 patients that were selected at random,who had been suffering from
heart failure to receive the gene. After the patients were injected, they were evaluated over
several months and improvements were documented. It is unclear if there will be availability for this gene therapy
for the current patient population with heart
failure but may be a possible solution for a group.
The U.S Centers for Disease Control & Prevention estimates that there are around 5.8 million
Americans that have heart failures. New Cases of about 670,000 are diagnosed annually. Statistics show that one out
of every 5 people that are said to have heart failure, pass on within a year.
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